Methods for characterizing enzyme inhibitors
US7897330B2 · kind B2 · utility
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17Claims
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Key dates
| Filing date | Aug 10, 2006 |
| Grant date | Mar 1, 2011 |
| Priority date | — |
| Expiry date | Jan 11, 2028 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N2500/02
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
Methods for characterizing a biochemical reaction and analysis of reaction products by establishing continuously variable concentration gradients of one or more reagents of the biochemical reaction are provided. Methods for determining mechanism of inhibition or activation, potency of inhibition or activation, or both of an enzyme inhibitor or activator, respectively, are also provided. The continuously variable concentration gradients can be established in a microfluidic chip.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.