Patent · US Active

I-CreI meganuclease variants with modified specificity, method of preparation and uses thereof

US7897372B2 · kind B2 · utility

17Cited by

2References

54Claims

0Family size

Assignee

CELLECTIS · FR

Inventors

Philippe Duchateau · Étampes, FR
Frederic Paques · Bourg-la-Reine, FR

Key dates

Filing date	Mar 15, 2006
Grant date	Mar 1, 2011
Priority date	—
Expiry date	Apr 9, 2028

Classification

Technology area (CPC A)Human Necessities
CPC primaryA61K48/00
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

Method of preparing 1-CreI meganuclease variants having a modified cleavage specificity, variants obtainable by said method and their applications either for cleaving new DNA target or for genetic engineering and genome engineering for non-therapeutic purposes. Nucleic acids encoding said variants, expression cassettes comprising said nucleic acids, vectors comprising said expression cassettes, cells or organisms, plants or animals except humans, transformed by said vectors.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.