39-desmethoxy-39-methyl derivatives of rapamycin
US7897608B2 · kind B2 · utility
6Cited by
15References
39Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Nov 19, 2008 |
| Grant date | Mar 1, 2011 |
| Priority date | — |
| Expiry date | May 29, 2029 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61P41/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention relates to novel 39-desmethoxy-39-methylrapamycin derivatives, methods for their production, and uses thereof. In a further aspect the present invention provides for the use of these 39-desmethoxy-39 -methylrapamycin derivatives in the treatment of cancer and/or B-cell malignancies, the induction or maintenance of immunosuppression, the treatment of transplantation rejection, graft vs. host disease, autoimmune disorders, diseases of inflammation, vascular disease and fibrotic diseases, the stimulation of neuronal regeneration or the treatment of fungal infections.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.