Process for preparation of 13,14-dihydro-PGF2 alpha derivatives
US7897793B2 · kind B2 · utility
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24Claims
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Key dates
| Filing date | Oct 18, 2007 |
| Grant date | Mar 1, 2011 |
| Priority date | — |
| Expiry date | Jun 17, 2028 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07C2601/08
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
The invention relates to a process for the preparation of 13,14-dihydro-PGF2α derivatives of R or S configuration at carbon 15, represented by the general formula (I), wherein the identity of the substituents is defined in the description. Compounds of the formula (I) are valuable biologically-active substances or intermediates in the preparation thereof. The invention especially relates to the process for preparation of 13,14-dihydro-15(R)-17-substituted-18,19,20-trinor-PGF2α, i.e., latanoprost.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.