Compositions for enhancing keratinocyte migration and epidermal repair via a receptor containing OSMRβ as a subunit, and applications thereof
US7901669B2 · kind B2 · utility
Assignees
Inventors
Key dates
| Filing date | Dec 15, 2005 |
| Grant date | Mar 8, 2011 |
| Priority date | — |
| Expiry date | Jun 30, 2026 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2501/2306
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention relates to the field of epidermal repair. More particularly, the invention concerns the use of a molecule able to activate a heteromeric receptor comprising OSMRβ as a subunit, for the preparation of a composition for activating in vitro and/or in vivo keratinocyte migration and/or the expression of anti-microbial peptides by the keratinocytes. In particular, the invention concerns the use of OSM and/or IL-17 and/or TNFα and/or IL-31, or agonists thereof, for the preparation of cosmetic or dermatologic compositions.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.