Polyvalent, primary HIV-1 glycoprotein DNA vaccines and vaccination methods
US7901690B2 · kind B2 · utility
Assignees
Inventors
Key dates
| Filing date | Dec 3, 2003 |
| Grant date | Mar 8, 2011 |
| Priority date | — |
| Expiry date | Jan 31, 2024 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2740/16234
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Polyvalent, primary isolate nucleic acid compositions for inducing an immune response against HIV is disclosed. The composition and methods described herein are for the use of a DNA composition that encodes one or more different HIV envelope glycoproteins. The DNA composition can encode an HIV Gag protein. The DNAs encoding one or more HIV proteins are a combination of different nucleic acids, such as DNA plasmids, generated from primary isolate DNA of different HIV major group genetic clades and/or different proteins. HIV protein compositions for inducing an immune response against HIV are disclosed. Methods fro using the protein compositions as boosts following administration of the DNA compositions are provided.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.