Markers for prenatal diagnosis and monitoring
US7901884B2 · kind B2 · utility
42Cited by
0References
27Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Apr 6, 2007 |
| Grant date | Mar 8, 2011 |
| Priority date | — |
| Expiry date | Jun 19, 2029 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12Q2600/156
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
This application provides the use of novel fetal markers for prenatal diagnosis and monitoring of certain pregnancy-related conditions. More specifically, the invention resides in the discovery that certain CpG islands located on fetal chromosome 21 demonstrate a methylation profile that is distinct from that of the corresponding CpG islands located on maternal chromosome 21. This application also provides kits for diagnosing or monitoring of the relevant conditions.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.