Process for production of Helicobacter pylori bacterioferritin

US7901907B2 · kind B2 · utility

Assignee

• THE PROVOST, FELLOWS AND SCHOLARS OF THE COLLEGE OF THE HOLY AND UNDIVIDED TRINITY OF QUEEN ELIZABETH NEAR DUBLIN · IE

Inventors

• William J. Byrne · Davis, US
• Dermot Kelleher · Dublin, IE
• Henry Windle · Dublin, IE
• Ross McManus · Dublin, IE

Key dates

• Filing date: Aug 25, 2006
• Grant date: Mar 8, 2011
• Expiry date: Aug 25, 2026

Classification

• Technology area (CPC A): Human Necessities
• CPC primary: A61K39/00
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

A nucleic acid sequence encoding all or part of an 18-19 kDa Helicobater pylori protein is described to which immunoreactivity is detected in H. pylori negative individuals. A process for the production of a recombinant form of this protein and its use, particularly as a vaccine to provide immunological protection against H. pylori infection are also described.