Process for the preparation of L-amino acids by overexpressing the tal gene encoding transaldolase

US7901913B2 · kind B2 · utility

Assignee

• EVONIK DEGUSSA GMBH · DE

Inventors

• Laurence K. Dunican · Galway, IE
• Ashling McCormack · Athlone, IE
• Cliona Stapelton · Roscrea, IE
• Kevin Burke · Marietta, US
• Bettina Mockel · Bielefeld, DE

Key dates

• Filing date: May 18, 2004
• Grant date: Mar 8, 2011
• Expiry date: Nov 16, 2025

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07K2319/00
• WIPO field: Biotechnology
• WIPO sector: Chemistry

Abstract

The invention is directed to DNA sequences from coryneform bacteria, particularly Corynebacterium glutamicum, which encode a protein having transaldolase enzymatic activity. The invention also encompasses processes for the fermentative production of L-amino acids using bacteria in which a gene encoding transaldolase is amplified.