MHC-antigen arrays for detection and characterization of immune responses
US7902121B2 · kind B2 · utility
14Cited by
8References
24Claims
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Key dates
| Filing date | May 27, 2004 |
| Grant date | Mar 8, 2011 |
| Priority date | — |
| Expiry date | Feb 23, 2028 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N33/56966
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
T cells are profiled with respect to their expression of antigen receptor. The cells are arrayed on a planar or three-dimensional substrate through binding to immobilized or partially diffused MHC-antigen complexes. The cells may further be characterized with respect to their ability to respond to external stimulus in the microenvironment. External stimuli include cell-cell interactions, response to factors, and the like.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.