Patent · US Active

6-substituted 2-(benzimidazolyl)purine and purinone derivatives for immunosuppression

US7902187B2 · kind B2 · utility

20Cited by

11References

12Claims

0Family size

Assignee

Wyeth, LLC · US

Inventors

Irina Neagu · Plainsboro, US
David Diller · Plainsboro, US
Celia Kingsbury · Cream Ridge, US
Adolph C. Bohnstedt · Burlington, US
Michael Ohlmeyer · Plainsboro, US
Vidyadhar Paradkar · Somerville, US
Nasrin Ansari · Monmouth Junction, US

Key dates

Filing date	Aug 22, 2008
Grant date	Mar 8, 2011
Priority date	—
Expiry date	Aug 22, 2028

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC07D473/40
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

The present invention provides novel purinones and purines useful for the prevention and treatment of autoimmune diseases, inflammatory disease, mast cell mediated disease and transplant rejection. The compounds are of the general formulae I and II shown below, in which Q is selected from the group consisting of CX and nitrogen; and A is chosen from the group consisting of H, (C1-C6) alkyl, heteroaryl, and aryl:

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.