Phenyl derivatives as factor XA inhibitors

US7902223B2 · kind B2 · utility

Assignee

• Merck Patent GmbH · DE

Inventors

• Dieter Dorsch · Ober-Ramstadt, DE
• Bertram Cezanne · Mörfelden, DE
• Christos Tsaklakidis · Weinheim, DE
• Werner Mederski · Zwingenberg, DE
• Johannes Gleitz · Darmstadt, DE
• Christopher Barnes · Bad Soden, DE

Key dates

• Filing date: Jul 12, 2002
• Grant date: Mar 8, 2011
• Expiry date: Oct 25, 2027

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D417/12
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

Novel compounds of the formula (I), in which D, W, X, Y, T and R1 are as defined in Patent Claim 1, are inhibitors of coagulation factor Xa and can be employed for the prophylaxis and/or therapy of thromboembolic diseases and for the treatment of tumors.