Dendrimeric peptides, pharmaceutical compositions and methods of using the same

US7902327B2 · kind B2 · utility

Assignee

• New York University School of Medicine · US

Inventors

• Neville Robert Kallenbach · New York, US
• Anne W. Young · Brooklyn, US
• Zhigang Liu · Xianyang, CN
• Chunhui Zhou · Beijing, CN

Key dates

• Filing date: May 22, 2008
• Grant date: Mar 8, 2011
• Expiry date: May 22, 2028

Classification

• Technology area (CPC Y): Emerging Cross-Sectional Technologies
• CPC primary: Y02A50/30
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

Novel dendrimeric peptide compounds are disclosed that have a formula represented by the following formula I:The compounds demonstrate antimicrobial activity and may be prepared as pharmaceutical compositions and used for the prevention and treatment of a variety of conditions in mammals including humans where microbial invasion is involved. The present peptides are particularly valuable as their effect is rapid, broad in spectrum and mostly indifferent to resistance provoked by standard antibiotics.