NK1 antagonists
US7902366B2 · kind B2 · utility
14Cited by
4References
19Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Feb 21, 2006 |
| Grant date | Mar 8, 2011 |
| Priority date | — |
| Expiry date | Feb 21, 2026 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D513/10
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A NK1 antagonist having the formula (I),wherein Ar1 and Ar2 are optionally substituted phenyl or heteroaryl, X1 is an ether, thio or imino linkage, R4 and R5 are not both H or alkyl, and the remaining variables are as defined in the specification, useful for treating a number of disorders, including emesis, depression, anxiety and cough. Pharmaceutical compositions. Methods of treatment and combinations with other agents are also disclosed.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.