Oral pharmaceutical formulation in the form of aqueous suspension for modified release of active principle(s)
US7906145B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | Apr 7, 2003 |
| Grant date | Mar 15, 2011 |
| Priority date | — |
| Expiry date | Sep 26, 2025 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K31/585
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The invention concerns liquid pharmaceutical formulations, for oral delivery, with modified release of active principle(s) excluding amoxicillin and consisting of suspensions of coated particles of active principles (microcapsules). The microcapsules constituting the dispersed phase of the suspension are designed, according to the invention, to enable modified release of the active principle(s), in accordance with a profile which remains unaltered during the shelf life of the liquid suspension. Therefor, the invention consists in selecting a coating composition specific to the microcapsules consisting of at least four components enabling preservation of said microcapsules in water without altering their properties of modified release of the active principle, said liquid phase being furthermore saturated with active principle(s).
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.