Magnetic nanoparticles, magnetic detector arrays, and methods for their use in detecting biological molecules

US7906345B2 · kind B2 · utility

Assignee

• The Board of Trustees of the Leland Stanford Junior University · US

Inventors

• Shan X. Wang · Portola Valley, US
• Robert L. White · Stanford, US
• Chris David Webb · Scotts Valley, US
• Guanxiong Li · Fremont, US

Key dates

• Filing date: Apr 22, 2004
• Grant date: Mar 15, 2011
• Expiry date: Mar 28, 2029

Classification

• Technology area (CPC Y): Emerging Cross-Sectional Technologies
• CPC primary: Y10T428/2991
• WIPO field: Measurement
• WIPO sector: Instruments

Abstract

Magnetic nanoparticles and methods for their use in detecting biological molecules are disclosed. The magnetic nanoparticles can be attached to nucleic acid molecules, which are then captured by a complementary sequence attached to a detector, such as a spin valve detector or a magnetic tunnel junction detector. The detection of the bound magnetic nanoparticle can be achieved with high specificity and sensitivity.