Substituted thiophene modulators of intracellular calcium
US7906553B2 · kind B2 · utility
4Cited by
3References
22Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Aug 26, 2009 |
| Grant date | Mar 15, 2011 |
| Priority date | — |
| Expiry date | Aug 26, 2029 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D495/04
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Described herein are compounds of Formula (I) having the structure:where A, J, R1, R4, Z and X are described herein; and pharmaceutical compositions containing such compounds, which modulate the activity of store-operated calcium (SOC) channels. Also described herein are methods of using such SOC channel modulators, alone and in combination with other compounds, for treating diseases or conditions that would benefit from inhibition of SOC channel activity.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.