Heterocyclic compounds as ccr2b antagonists
US7906645B2 · kind B2 · utility
1Cited by
3References
15Claims
0Family size
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Key dates
| Filing date | Dec 19, 2005 |
| Grant date | Mar 15, 2011 |
| Priority date | — |
| Expiry date | Aug 17, 2027 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D417/06
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
Compounds of formula (I) Q-L-W—C(═X)—Z—P wherein Q is an amine of the formula —N(R1)(R2); L is an alkyl or heterocyclyl-alkyl linker; W is a 6- or 7-membered aliphatic ring comprising ring atoms Y1 and Y2 which are linked to groups L and C(X) respectively and Y1 and Y2 are independently selected from N and C; X is O, N, N—CN or S; Z is NR3; P is an optionally substituted monocyclic or bicyclic aryl or heteroaryl group; and pharmaceutically acceptable salts or solvates thereof, are useful in the treatment of C-C chemokine mediated conditions.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.