Methods for monitoring reactions in zero mode waveguides

US7907800B2 · kind B2 · utility

Assignee

• PACIFIC BIOSCIENCES OF CALIFORNIA, INC. · US

Inventors

• Mathieu Foquet · San Jose, US
• Paul Peluso · East Palo Alto, US
• Stephen Turner · Menlo Park, US
• Daniel Roitman · Menlo Park, US
• Geoffrey Otto · Brookline, US

Key dates

• Filing date: Dec 22, 2008
• Grant date: Mar 15, 2011
• Expiry date: Jun 15, 2029

Classification

• Technology area (CPC G): Physics
• CPC primary: G01N2021/7713
• WIPO field: Measurement
• WIPO sector: Instruments

Abstract

Methods for monitoring reactions are provided, including methods involving monitoring reactions in zero mode waveguide substrates. The zero mode waveguide substrates have zero mode waveguides wherein the core extends through the cladding layer at least partially into the transparent substrate.