Mobile phase dilution scheme for enhanced chromatography
US7909994B2 · kind B2 · utility
6Cited by
21References
6Claims
0Family size
Assignee
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Key dates
| Filing date | Mar 18, 2010 |
| Grant date | Mar 22, 2011 |
| Priority date | — |
| Expiry date | Mar 18, 2030 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N2030/347
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
A method and device for increasing the loading capacity of a chromatography column through dilution of a mobile phase at the head of the column. A strong mobile phase is provided for dissolving a sample. A sample is injected into the strong mobile phase, and subsequently diluted with a weak mobile phase. The resulting sample-containing weak mobile phase is passed through a chromatography column for retention and separation of the components of the sample.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.