Human cancer-relating genes, the products encoded thereby and applications thereof

US7910711B2 · kind B2 · utility

Assignee

• Peking University · CN

Inventors

• Rouli Zhou · Beijing, CN
• Genze Shao · Beijing, CN
• Xinrong Liu · Beijing, CN
• Qingyun Zhang · Jiexi, CN
• Jingan Rui · Beijing, CN
• Ye Zhang · Shanghai, CN
• Yueying Jin · Beijing, CN
• Ming Lin · Beijing, CN
• Sha Zhang · Ithaca, US

Key dates

• Filing date: Dec 24, 2003
• Grant date: Mar 22, 2011
• Expiry date: Jan 21, 2026

Classification

• Technology area (CPC G): Physics
• CPC primary: G01N2333/705
• WIPO field: Measurement
• WIPO sector: Instruments

Abstract

The invention discloses a human cancer-related gene, LAPTM4B, its encoded products and their applications thereof. This human cancer-related gene provided by this invention comprises one of the following nucleotide sequences: (1) SEQ ID No: 1, SEQ ID No: 2, SEQ ID No: 3, SEQ ID No: 6, or SEQ ID No: 8 in the sequence listings; (2) Polynucleotides that encode the protein sequences of SEQ ID No: 4, SEQ ID No: 5, or SEQ ID No: 7 in the sequence listings; (3) DNA sequences having above 90% homology with the DNA sequences specified by SEQ ID No: 1, SEQ ID No: 2, SEQ ID No: 3, SEQ ID No: 6, or SEQ ID No: 8 in the sequence listings, and these DNA sequences encode the proteins with the same or similar functions. This invention enables the developments of new anti-cancer approaches and new anti-cancer medicines. It would create a significant impact on human society.