Patent · US Active

Polyanion for improved nucleic acid amplification

US7910720B2 · kind B2 · utility

4Cited by

19References

9Claims

0Family size

Assignee

Roche Diagnostics Operations, Inc. · US

Inventors

Waltraud Ankenbauer · Penzberg, DE
Dieter Heindl · Munich, DE
Frank Laue · Kempten (Allgäu), DE
Eva Walter · Bichl, DE
Renate Kolb · Iffeldorf, DE

Key dates

Filing date	Aug 25, 2009
Grant date	Mar 22, 2011
Priority date	—
Expiry date	Sep 30, 2029

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC12Q1/6848
WIPO fieldOrganic fine chemistry
WIPO sectorChemistry

Abstract

The present invention is directed to a novel chemical compound comprising the structure [Xx-(CH2)m-phosphate-Yy]n, characterized in that 3≦m≦6, 30≦n≦60, each x and y is independently from each other 0 or 1, each X and Y is independently from each other any photometrically measurable entity; provided that the terminal X can also be an —OH group or a phosphate group, and further provided that the terminal Y can also be an —OH group. Such a compound can be used as a suitable hot start additive for PCR based amplification of nucleic acids.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.