Phosphonate and phosphinate pyrazolylamide glucokinase activators

US7910747B2 · kind B2 · utility

Assignee

• Bristol-Myers Squibb Company · US

Inventors

• Denis E. Ryono · Princeton, US
• Peter Cheng · Princeton, US
• Scott A. Bolton · Newtown, US
• Sean Chen · Sunnyvale, US
• Yan Shi · Flourtown, US
• Wei Meng · Pennington, US
• Joseph A. Tino · Lawrenceville, US

Key dates

• Filing date: Jun 28, 2007
• Grant date: Mar 22, 2011
• Expiry date: Jun 28, 2027

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07F9/6518
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

Pyrazoloamides are provided which are phosphonate and phosphinate glucokinase activators that are useful in treating diabetes and related diseases and have the structurewhereinis a pyrazoyl ring;