Fluorescence-based scanning imaging device
US7911670B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | Nov 7, 2006 |
| Grant date | Mar 22, 2011 |
| Priority date | — |
| Expiry date | Jun 7, 2027 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N2201/101
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
A device for analysing a specimen by fluorescence includes a confocal microscope, illumination means capable of emitting a light beam that converges, by means of an objective, on a focal spot, means for successively positioning the focal spot at various points on the specimen during analysis. The confocal microscope includes an objective mounted on a movable rapid-scan carriage driven in a reciprocating linear movement along a traverse direction by a rotating motor by means of a device of the connecting rod type. The specimen is placed on a movable support driven in a longitudinal movement and is able to move along the axis of the objective of the microscope in order to position the specimen relative to the focal spot. The excitation light spectrum is spread over the surface of the specimen in such a way that the excitation light reflected by the specimen and corresponding to the wavelengths close to fluorescence converge on points that are sufficiently distant from a diaphragm positioned in front of a device for measuring the fluorescence.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.