Patent · US Active

Keratinocytes expressing exogenous angiogenic growth factors

US7915042B2 · kind B2 · utility

4Cited by
12References
3Claims
0Family size

Assignee

Inventors

Key dates

Filing dateFeb 25, 2009
Grant dateMar 29, 2011
Priority date
Expiry dateApr 18, 2029

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC12N2502/99
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

The present invention relates to in vitro cultured skin tissue, and in particular to cultured skin tissue comprising exogenous genes encoding angiogenic growth factors. In some embodiments, the keratinocytes express exogenous angiopoietin-1 or a member of the VEGF family, preferably VEGF-A. In particularly preferred embodiments, the keratinocytes are incorporated into cultured skin tissue.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.