Proteasome inhibitors and methods of using the same
US7915236B2 · kind B2 · utility
2Cited by
30References
55Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Jul 1, 2009 |
| Grant date | Mar 29, 2011 |
| Priority date | — |
| Expiry date | Jul 1, 2029 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07F5/025
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention provides boronic acid compounds, boronic esters, and compositions thereof that can modulate apoptosis such as by inhibition of proteasome activity. The compounds and compositions can be used in methods of inducing apoptosis and treating diseases such as cancer and other disorders associated directly of indirectly with proteasome activity.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.