Patent · US Active

Method for preparing phenyl acetic acid derivatives

US7915421B2 · kind B2 · utility

0Cited by

3References

12Claims

0Family size

Assignee

Cilag GmbH · CH

Inventors

Rainer Heck · Glückstadt, DE
Michael Justus · Beloit, US
Roland Müller · Aarau, CH
Thomas Otten · Zürich, CH
Martin Rettig · Schwanau, DE

Key dates

Filing date	May 13, 2004
Grant date	Mar 29, 2011
Priority date	—
Expiry date	Apr 27, 2027

Classification

Technology area (CPC Y)Emerging Cross-Sectional Technologies
CPC primaryY02P20/55
WIPO fieldOrganic fine chemistry
WIPO sectorChemistry

Abstract

Method for preparing (S)(+)phenyl acetic acid derivatives having the general formula (I):wherein R1 is a linear or branched alkyl group with 1-6 carbon atoms or substituted benzyl group, and R2 is methyl, ethyl or propyl group said method, characterised in that a compound of the general formula (II):wherein R1 is as given above, and R3 is a nucleofuge, or a suitable salt of a compound of the general formula (II) is reacted with a compound having the general formula (III):wherein R2 is as given above, and R4 is hydrogen or a nucleofuge that can be removed hydrolytically, and the protective group R4 that may be present, may be subsequently removed hydrolytically.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.