Patent · US Active

Methods and compositions for inactivating alpha 1,6 fucosyltransferase (FUT8) gene expression

US7919313B2 · kind B2 · utility

6Cited by

27References

24Claims

0Family size

Assignee

Sangamo Biosciences, Inc. · US

Inventors

Trevor Collingwood · Chesterfield, US
Gregory J. Cost · Berkeley, US

Key dates

Filing date	Jul 10, 2008
Grant date	Apr 5, 2011
Priority date	—
Expiry date	Apr 13, 2029

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC12N2800/80
WIPO fieldBiotechnology
WIPO sectorChemistry

Abstract

Disclosed herein are methods and compositions for inactivating a FUT8 gene, using fusion proteins comprising a zinc finger protein and a cleavage domain or cleavage half-domain. Polynucleotides encoding said fusion proteins are also provided, as are cells comprising said polynucleotides and fusion proteins.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.