Hematopoietic stem cell identification and isolation
US7919316B2 · kind B2 · utility
0Cited by
4References
12Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Feb 19, 2009 |
| Grant date | Apr 5, 2011 |
| Priority date | — |
| Expiry date | Apr 12, 2029 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N5/0647
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
The present invention relates to methods of identifying, collecting and isolating hematopoietic stem cells (HSCs) and compositions of purified HSCs. Specifically, the present invention provides methods of isolating and purifying CD150+ HSCs, CD48− HSCs, and CD244− HSCs. The present invention also relates to purified cell samples with enriched CD150+ HSCs, CD48− HSCs, and CD244− HSCs populations, as well as methods of treating subjects with such compositions.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.