Nanotubes as mitochondrial uncouplers
US7919699B2 · kind B2 · utility
Assignee
Inventor
Key dates
| Filing date | May 5, 2006 |
| Grant date | Apr 5, 2011 |
| Priority date | — |
| Expiry date | Feb 27, 2028 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10S977/915
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A method of uncoupling mitochondria in a subject including administering nanotubes to the subject in a therapeutically effective amount, wherein the nanotubes are self-rectifying is provided. A method of decreasing reactive oxygen species and decreasing detrimental loading of Ca2+ into mitochondria is provided, including administering a pharmaceutically effective amount of nanotubes into the subject. A method of reducing weight, treating cancer, reducing the effects of traumatic brain injury, or reducing the effects of ageing, in a subject including administering a pharmaceutically effective amount of nanotubes into the subject is also provided.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.