Patent · US Active

Substituted pyrrole derivatives and their use as HMG-CO inhibitors

US7923467B2 · kind B2 · utility

0Cited by
152References
23Claims
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Assignee

Inventors

Key dates

Filing dateMay 28, 2004
Grant dateApr 12, 2011
Priority date
Expiry dateAug 21, 2027

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC07D413/04
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

The present invention relates to substituted pyrrole derivatives, which can be used as 3-hydroxy-3-methylglutaryl-coenzyme A (HMG-CoA) reductase inhibitors. Compounds disclosed herein can function as cholesterol lowering agents and can be used for the treatment of cholesterol-related diseases and related symptoms. Processes for the preparation of disclosed compounds are provided, as well as pharmaceutical compositions containing the disclosed compounds, and methods of treating cholesterol-related diseases and related symptoms.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.