Phenyl-substituted pyrimidine compounds useful as kinase inhibitors

US7923556B2 · kind B2 · utility

Assignee

• Bristol-Myers Squibb Company · US

Inventors

• Stephen T. Wrobleski · Whitehouse Station, US
• Shuqun Lin · Newtown, US
• Katerina Leftheris · Skillman, US
• Liqi He · West Chester, US
• Steven P. Seitz · Swarthmore, US
• Tai-An Lin · Pequannock, US
• Wayne Vaccaro · Yardley, US

Key dates

• Filing date: Sep 30, 2009
• Grant date: Apr 12, 2011
• Expiry date: Sep 30, 2029

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D417/04
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

Compounds having the formula (I),and pharmaceutically acceptable salts, and solvates thereof, are useful as kinase inhibitors, wherein: Also disclosed are pharmaceutical compositions containing compounds of formula (I), and methods of treating conditions associated with the activity of p38 kinase and/or conditions associated with the activity of LIM kinase.