Method for water-fat separation and T2* estimation in an MRI system employing multiple fat spectral peaks and fat spectrum self-calibration
US7924003B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | Apr 17, 2008 |
| Grant date | Apr 12, 2011 |
| Priority date | — |
| Expiry date | Jan 31, 2029 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01R33/56527
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
NMR signal contributions from water and fat are separated using a model of the fat resonant frequency spectrum that has multiple resonant peaks. The relative frequencies of the multiple fat spectrum peaks are known a priori and their relative amplitudes are determined using a self-calibration process. With the determined relative amplitudes of the fat spectrum peaks, acquired NMR signals are modeled. Using this model and NMR signal data acquired at a plurality of echo times (TE), the signal contribution from multiple fat spectrum peaks is separated from the acquired NMR signal data. A combined image is alternatively produced from weighted contributions of the separated water and fat images. Additionally, a more accurate estimation of the apparent relaxation time and rate (T*2 and R*2, respectively) is alternatively performed.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.