Tablets quickly disintegrated in oral cavity
US7927623B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | Feb 12, 2002 |
| Grant date | Apr 19, 2011 |
| Priority date | — |
| Expiry date | Jul 12, 2025 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K9/1635
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Intraorally rapidly disintegrating tablets which, when ingested, disintegrates in the oral cavity rapidly without presenting unpleasant taste, can be quickly absorbed in the digestive tract and express efficacy are provided. The intraorally rapidly disintegrating tablets contain a drug being hardly water-soluble under neutral or alkaline conditions and being highly water-soluble under acidic conditions yet presenting unpleasant taste, which tablets can be prepared by combining the medicinal substance with a water-soluble acidic substance, coating either or both of the substances with a water-soluble coating agent being insoluble in alcoholic solvent, further adding a water-soluble binding agent being soluble in alcoholic solvent and a water-soluble saccharide, subjecting the resultant mixture to compression, and treating the products with an alcoholic solvent.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.