Methods for in vitro expansion of hematopoietic stem cells
US7927785B2 · kind B2 · utility
15Cited by
19References
21Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | May 12, 2005 |
| Grant date | Apr 19, 2011 |
| Priority date | — |
| Expiry date | Jan 19, 2026 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2501/70
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
The invention relates to methods of obtaining compositions for generating multipotent hematopoietic stem progenitor cells comprising expansion of hematopoietic stem cells in the presence of HDACI and IDM. Methods of obtaining compositions enriched in hematopoietic megakaryocyte progenitor cells are also provided. Compositions enriched for stem cells and populations of cells obtained therefrom are also provided by the invention.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.