Patent · US Active

Process for the determination of lipoproteins in body fluids

US7927878B2 · kind B2 · utility

8Cited by

5References

22Claims

0Family size

Assignee

LipoFIT Analytic GmbH · DE

Inventors

Werner Kremer · Pentling, DE
Hans Robert Kalbitzer · Regensburg, DE
Fritz Huber · Regensburg, DE

Key dates

Filing date	Jun 1, 2005
Grant date	Apr 19, 2011
Priority date	—
Expiry date	Jul 21, 2028

Classification

Technology area (CPC Y)Emerging Cross-Sectional Technologies
CPC primaryY10T436/24
WIPO fieldMeasurement
WIPO sectorInstruments

Abstract

The invention describes a process for the determination of the concentration distribution and size distribution of lipoprotein classes in body fluids, e.g. blood. For this purpose, NMR spectra of a sample to be analysed are measured by magnetic field gradient intensities and temperatures under different diffusion-weighted measuring conditions selected according to different pulse programs (e.g. PFG-STE, PFG-LED etc) and consequently in a differentiated manner according to the relaxation times. The different effects of these measuring conditions on the intensity/line form of the NMR signals of the individual lipoprotein classes are determined and permit the determination of a concentration distribution/size distribution of the individual lipoprotein classes.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.