Patent · US Active

Use of neuropeptides for traumatic cartilage injury

US7928059B2 · kind B2 · utility

0Cited by
3References
4Claims
0Family size

Assignee

Inventors

Key dates

Filing dateMay 10, 2006
Grant dateApr 19, 2011
Priority date—
Expiry dateJun 17, 2028

Classification

  • Technology area (CPC Y)Emerging Cross-Sectional Technologies
  • CPC primaryY10S530/84
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

Disclosed are a method and a corresponding pharmaceutical composition for treating damaged cartilage and subchondral bone. Neurogenic compounds in general and neuropeptides in particular have been found to be highly effective in stimulated repair of cartilage and bone damaged due to traumatic injury, ligament disease, and disuse. Preferred active ingredients for use in the method and corresponding pharmaceutical composition include calcitonin gene-related peptide (CGRP), cholecystokinin (CCK), dynorphin, enkephalin, galanin, neuropeptide Y (NPY), neurotensin, somatostatin, substance P (SP), thyrotropin-releasing hormone (TRH), vasoactive intestinal peptide (VIP).

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.