Oxabispidine compounds for the treatment of cardiac arrhythmias

US7928225B2 · kind B2 · utility

Assignee

• ASTRAZENECA AB · SE

Inventors

• Annika Bjore · Stenungsund, SE
• David Cladingboel · Mountsorrel, GB
• Gareth Ensor · Loughborough, GB
• Adam Herring · Coalville, GB
• Johan Kajanus · Timrå, SE
• Robert Lundqvist · Timrå, SE
• Christina Olsson · Mölndal, SE
• Carl-Gustav Sigfridsson · Timrå, SE
• Gert Strandlund · Lindome, SE

Key dates

• Filing date: Jun 12, 2006
• Grant date: Apr 19, 2011
• Expiry date: Nov 28, 2027

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07C309/73
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

There is provided compounds of formula I, wherein R1, R2, R3, R41 to R46, X, Y and Z have meanings given in the description, which compounds are useful in the prophylaxis and in the treatment of arrhythmias, in particular atrial and ventricular arrhythmias.