Method for the treatment of metabolic disorders

US7932290B2 · kind B2 · utility

Assignee

• Wellstat Biologics Corporation · US

Inventors

• Kirvin L. Hodge · Laurel, US
• Shalini Sharma · Gaithersburg, US
• Albert Lee · Hickory, US
• Reid W. von Borstel · Potomac, US

Key dates

• Filing date: Aug 31, 2009
• Grant date: Apr 26, 2011
• Expiry date: Aug 31, 2029

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07C69/92
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

Agents useful for the treatment of various metabolic disorders, such as insulin resistance syndrome, diabetes, hyperlipidemia, fatty liver disease, cachexia, obesity, atherosclerosis and arteriosclerosis are disclosed.wherein n is 1 or 2; m is 0, 1, 2, 4, or 5; q is 0 or 1; t is 0 or 1; R2 is alkyl having from 1 to 3 carbon atoms; R3 is hydrogen, halo, alkyl having from 1 to 3 carbon atoms, or alkoxy having from 1 to 3 carbon atoms;