Molecular transporter compositions comprising dendrimeric oligoguanidine with a triazine core that facilitate delivery into cells in vivo
US7935816B2 · kind B2 · utility
13Cited by
1References
7Claims
0Family size
Assignee
Inventor
Key dates
| Filing date | Oct 25, 2007 |
| Grant date | May 3, 2011 |
| Priority date | — |
| Expiry date | Oct 30, 2028 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D403/04
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Preparations of novel molecular transporter compositions and their use for transporting bioactive substances into cells in living animals are disclosed. To afford in vivo delivery, the composition is covalently linked to the bioactive substance and the resultant composite structure is introduced into the subject. The transporter composition includes multiple guanidine moieties on a dendrimeric scaffold having a triazine core.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.