Patent · US Active

Uses of IL-12 in hematopoiesis

US7939058B2 · kind B2 · utility

3Cited by

2References

15Claims

0Family size

Assignee

University of Southern California · US

Inventors

Tingchao Chen · Monterey Park, US
Yi Zhao · South Pasadena, US
W. French Anderson · Bethesda, US

Key dates

Filing date	Jul 6, 2004
Grant date	May 10, 2011
Priority date	—
Expiry date	Jul 22, 2026

Classification

Technology area (CPC A)Human Necessities
CPC primaryA61N2005/1098
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

Methods for enhancing or stimulating hematopoiesis including the step of administering Interleukin-12 (IL-12) to yield hematopoietic recovery in a mammal in need. Preferred methods include the step of administering IL-12 as an adjuvant therapy to alleviate the hematopoietic toxicities associated with one or more treatment regimens used to combat a disease state. Other methods include administering IL-12 to ameliorate various hematopoietic deficiencies. Still other methods are directed to uses of IL-12 for in-vivo proliferation of hematopoietic repopulating cells, hematopoietic progenitor cells and hematopoietic stem cells. Other disclosed methods are directed to uses of Il-12 for bone marrow preservation or recovery.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.