System and method for the treatment of cancer, including cancers of the central nervous system
US7939090B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | Oct 20, 2004 |
| Grant date | May 10, 2011 |
| Priority date | — |
| Expiry date | Oct 20, 2024 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K2239/47
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The invention relates to the treatment of cancer, and particularly to the treatment of cancers of the central nervous system, such as glioblastoma multiforme. A dual therapeutic approach is provided, including the administration of a dendritic cell-based cancer vaccine and a regimen of chemotherapy. The two therapies may be administered concurrently with one another and/or with an initial vaccination preceding chemotherapy. In various embodiments, the dendritic cell-based cancer vaccine includes either primed or unprimed dendritic cells; for instance, the dendritic cells may be autologous tumor antigen-presented dendritic cells. The dual therapeutic approach of the instant invention beneficially influences the chemosensitivity of a mammal with cancer.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.