Rapid thermocycler with movable cooling assembly
US7939312B2 · kind B2 · utility
25Cited by
6References
16Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Apr 9, 2007 |
| Grant date | May 10, 2011 |
| Priority date | — |
| Expiry date | Mar 5, 2029 |
Classification
- Technology area (CPC B)Performing Operations; Transporting
- CPC primaryB01L2300/1894
- WIPO fieldChemical engineering
- WIPO sectorChemistry
Abstract
Methods and apparatus for effecting rapid thermocycling in connection with the polymerase chain reaction are disclosed. A sample assembly having a relatively small thermal mass is heated to desired PCR operating temperatures, and a separate cooling assembly is used to rapidly lower the temperature as required. In one embodiment, a sample assembly with an integrated heating element is isolated from a relatively large thermal mass cold sink when the temperature of a sample is to be raised or maintained, and brought in contact with the cold sink when the temperature is desired to be lowered.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.