Amphiphilic derivatives for the production of vesicles, micelles and complexants, and precursors thereof

US7939562B2 · kind B2 · utility

Assignee

• BEN GURION UNIVERSITY OF THE NEGEV RESEARCH AND DEVELOPMENT AUTHORITY · IL

Inventors

• Sarina Grinberg · Meitar, IL
• Charles Linder · Rehovot, IL
• Zeev Wiesman · Rahat, IL
• Eliahu Heldman · Rehovot, IL
• Victoria Kolot · Beer Sheva, IL

Key dates

• Filing date: Jan 16, 2002
• Grant date: May 10, 2011
• Expiry date: Jun 8, 2024

Classification

• Technology area (CPC A): Human Necessities
• CPC primary: A61K9/1075
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

Amphiphilic derivatives composed of at least one fatty acid chain are derived from natural vegetable oils such as vernonia oil, lesquerella oil and castor oil, in which the several reactive groups such as epoxy, hydroxy and double bonds can be modified to polar and ionic groups. The head group of the amphiphilic derivative may be in the main fatty acid chain or in a side chain. The amphiphiles are useful for the formation of vesicles and micelles and for use as complexants and surfactants.