Patent · US Active

Process for the preparation of levetiracetam

US7939676B2 · kind B2 · utility

1Cited by

4References

14Claims

0Family size

Assignee

ZACH SYSTEMS S.P.A. · IT

Inventors

Corrado Colli · Pioltello, IT
Massimiliano Forcato · Monselice, IT
Livius Cotarca · Palmanova, IT

Key dates

Filing date	Sep 17, 2009
Grant date	May 10, 2011
Priority date	—
Expiry date	Sep 17, 2029

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC07D207/27
WIPO fieldOrganic fine chemistry
WIPO sectorChemistry

Abstract

A process for the manufacturing of levetiracetam, wherein said process comprises the steps of: (1) reacting the (−)-(S)-alpha-ethyl-2-oxo-1-pyrrolidine acetic acid with a substoichiometric amount of an activating agent in an alcoholic solvent, and (2) subjecting the resulting reaction solution of step (1) to an ammonolysis process with gaseous ammonia.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.