Diagnostic assay for anti-von Willebrand Factor cleaving protease (ADAMTS13) antibodies
US7943326B2 · kind B2 · utility
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8Claims
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Key dates
| Filing date | Jul 2, 2010 |
| Grant date | May 17, 2011 |
| Priority date | — |
| Expiry date | Jul 2, 2030 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12Q1/56
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
This invention relates to a kit to be used in an assay system for determination of an anti-von Willebrand Factor-cleaving protease (“anti-vWF-cp”) antibody in a sample. The kit comprises vWF-cp and/or vWF-fragment(s) immobilized on a solid phase. The kit can be used in a method for determination of anti-vWF-cp antibodies from a patient, for the diagnosis of disorders associated with the occurrence of anti-vWF-cp-antibodies, and the differentiation of various forms of thrombotic microangiopathy.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.