Patent · US Active

Imiquimod production process

US7943771B2 · kind B2 · utility

1Cited by

7References

20Claims

0Family size

Assignee

Chemagis Ltd. · IL

Inventors

Vladimir Naddaka · Netanya, IL
Eyal Klopfer · Nes Ziona, IL
Shady Saeed · Haifa, IL
Stephen Cherkez · Ramat Gan, IL
Oded Arad · Rehovot, IL

Key dates

Filing date	Jan 24, 2007
Grant date	May 17, 2011
Priority date	—
Expiry date	Dec 18, 2029

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC07D471/04
WIPO fieldOrganic fine chemistry
WIPO sectorChemistry

Abstract

Provided is a process for producing highly pure 4-amino-1-isobutyl-1H-imidazo[4,5-c]quinoline (imiquimod), which includes reacting 4-chloro-1-isobutyl-1H-imidazo[4,5-c]quinoline with a non-gaseous amine precursor. Also provided are methods for isolating highly pure imiquimod. Further provided are intermediates useful in the production of imiquimod, methods for producing such intermediates, and methods for obtaining imiquimod from such intermediates.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.