Methods for expression and purification of pegylated recombinant human growth hormone containing a non-naturally encoded keto amino acid
US7947473B2 · kind B2 · utility
19Cited by
164References
4Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Jan 31, 2008 |
| Grant date | May 24, 2011 |
| Priority date | — |
| Expiry date | Jan 31, 2028 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61P5/06
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
The present invention relates generally to the production, purification, and isolation of human growth hormone (hGH). More particularly, the invention relates to the production, purification, and isolation of substantially purified hGH comprising non-naturally encoded amino acids and hGH from recombinant host cells or culture medium including, for example, yeast, insect, mammalian and bacterial host cells. The process of the present invention is also useful for purification of hGH linked to polymers or other molecules.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.