Synthesis and anti-proliferative effect of benzimidazole derivatives
US7947723B2 · kind B2 · utility
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4Claims
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Key dates
| Filing date | Jan 30, 2009 |
| Grant date | May 24, 2011 |
| Priority date | — |
| Expiry date | Jan 30, 2029 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D487/04
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
This invention provides for compounds, compositions, and methods that involve anti-proliferative and anti-neoplastic activity in cancer cells. In particular, a series of benzimidazole, purine, imidazopyridine, and imidazopyrizine compounds having selected substitution patterns are disclosed, and the activity of various subject compounds is demonstrated. For example, the invention provides compounds having the general formula:their pharmaceutical compositions, and methods of treatment using the subject compounds and compositions.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.