Patent · US Active

Antibodies that bind specifically to human RON protein

US7947811B2 · kind B2 · utility

9Cited by

6References

7Claims

0Family size

Assignee

ImClone LLC · US

Inventors

Daniel Pereira · Los Angeles, US
Jennifer O'Toole · Valley Stream, US

Key dates

Filing date	Nov 21, 2008
Grant date	May 24, 2011
Priority date	—
Expiry date	Apr 28, 2029

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC07K2317/92
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

The invention provides antibodies or fragments thereof, including human antibodies, specific for Macrophage-Stimulating Protein Receptor (MSP-R or RON), which inhibit RON activation. Also provided are methods to inhibit RON, particularly the use of RON antibodies to treat diseases such as cancer.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.